Testosterone Levels in Women Testing & Therapy FAs new policy on transgender women includes reduced testosterone levels and match observation The Athletic In women, normal testosterone levels range from 15 to 70 nanograms per deciliter (ng/dL) of blood. When it comes to sex hormones, women are driven by estrogen, and men are driven by testosterone, right? Well, everyone has both — it’s just that females have more estrogen while males have more testosterone. However, this seems to be unrelated to menopause development (39–42). We here report reduced serum testosterone levels in cis women with PBC compared with healthy age- and sex- matched controls. This is in accordance with reports from other autoimmune diseases, including SLE, MS, and RA, in which lower serum levels of testosterone have previously been reported (18, 19). Furthermore, testosterone serum levels negatively correlated with concentrations of proinflammatory cytokines IFN-γ and TNF, which are related to T cell activation (Figure 1). There was no correlation between serum testosterone levels and liver stiffness, age, or BMI, suggesting that the observed immune phenotypes are unlikely to be confounded by these variables. Since T cells play an important role in the pathogenesis of AIH and PBC, we further investigated the effect of testosterone on human and murine T cells. However, abnormally low or high levels of testosterone can have detrimental effects on women’s health and should be addressed. High or low testosterone symptoms women experience can be difficult to spot, but understanding signs that indicate an imbalance is an important step in regaining hormonal health. So, keep reading to learn more about unhealthy levels of testosterone in women—including causes and symptoms, as well as how to check testosterone levels. High or low testosterone levels in women produce various health effects. Certain medical conditions, such as polycystic ovary syndrome (PCOS), can also cause an increase in testosterone levels in women. It’s possible for a woman’s testosterone production to be too high or too low. And because testosterone is a key hormone in the body—in women and men alike—abnormal testosterone levels can have quite an impact on the health and well-being of a pre-or post-menopausal woman. Understanding the impact of testosterone and estrogen on various aspects of health can help women recognize and manage symptoms of hormonal imbalances, promoting overall well-being and improving quality of life. It’s important to note that these ranges can vary depending on the lab and testing methods used. It is important for women to be aware of the potential symptoms of low or high testosterone levels and to seek medical advice if they suspect any imbalances. A healthcare professional can provide a proper diagnosis and develop a personalized treatment plan to address any hormonal imbalances and improve overall health and well-being. If you have high levels of testosterone, it’s important to speak with your healthcare provider to learn about treatment options. In some cases, hormone therapy or medication can help restore your levels to a normal range. Testosterone production starts ramping up between the ages of 6