Low Testosterone Symptoms: Mood, Weight, and Sex Low Testosterone Symptoms: Mood, Weight, and Sex In both instances, testosterone replacement therapy is the primary form of treatment. Male hypogonadism is a deficiency in the sex hormone testosterone in adult males and male children. Testosterone supports muscle mass, libido, energy levels, mood, focus, sleep quality, bone density, metabolic health, and more, says Houman. Infections like mumps, stress, heavy drinking, obesity, trauma to the testes and certain prescription drugs can all have a negative impact. Fat cells produce an enzyme called aromatase, which converts testosterone to estrogen— and an imbalance in your testosterone and estrogen levels can increase body fat. High aromatase and estrogen activity reduces the production of gonadotropin-releasing hormone (GnRH), which in turn reduces testosterone production. Many men with diagnosed testosterone deficiency notice a dramatic improvement in their mood after starting testosterone replacement treatment, says Calvert. If you’re noticing it’s hard to get and keep an erection, it’s worth getting your testosterone levels checked. All this means that your total testosterone level on its own, while important to test and monitor before and during any treatment, can’t tell you whether you are suffering from low testosterone or not. In order to reach a diagnosis of low testosterone or testosterone deficiency syndrome you will need a full blood test covering a wide spectrum of measures to reach a complete understanding of your hormonal health. Your doctor should also take a complete medical history and  undertake a physical examination, in addition to a detailed discussion of your symptoms. This is where to inject testosterone thigh exclude the possibility that your symptoms might be related to other health problems. The mortality of men with testosterone deficiency is significantly higher than among men with normal testosterone levels. But, it is unclear whether replacing testosterone to a normal level reduces that increased mortality. Treatment is largely focused on the treatment of symptoms, not the specific testosterone level. Symptoms of low testosterone (“low T”) are easily missed, especially in older males who experience non-specific symptoms like fatigue, weight gain, low libido, and erectile dysfunction (ED). Spotting low T can even be more challenging in younger males, who often complain of tiredness in the absence of low libido and ED. If low testosterone is caused by your pituitary gland rather than your testicles, TRT would be of little help as it wouldn’t alter levels of LH or FSH in your blood. If infertility is a concern, injections of LH and FSH may be prescribed to help stimulate sperm production. The depression directly caused by low T can be amplified when low libido and erectile dysfunction start to affect a person’s sex life. If a male with low testosterone is trying to raise testosterone and maintain or improve fertility, then fertility-sparing regimens are recommended. Generally, these are with off-label use of drugs such as clomiphene citrate or human chorionic gonadotropin (HCG). While higher scores provide stronger evidence of male hypogonadism, the ADAM test has its limitations and may not be as